Research Articles
Decoding Hepatocellular Carcinoma: A Comprehensive Guide to Non-Coding RNA Sequencing Analysis
This article provides a comprehensive exploration of RNA sequencing for profiling non-coding RNAs (ncRNAs) in hepatocellular carcinoma (HCC) tissues.
Strategies to Reduce False Positives in lncRNA Biomarker Detection for Hepatocellular Carcinoma
This article addresses the critical challenge of false positives in the detection of long non-coding RNA (lncRNA) biomarkers for Hepatocellular Carcinoma (HCC), a major obstacle to their clinical adoption.
CRISPR Screening for lncRNA Functional Characterization in Hepatoma Cells: Methods, Applications, and Clinical Translation
Long non-coding RNAs (lncRNAs) are critical regulators in hepatocellular carcinoma (HCC) pathogenesis, yet their functional characterization remains challenging.
Circulating lncRNAs as Liquid Biopsy Biomarkers in Liver Cancer: From Mechanism to Clinical Translation
Liquid biopsy analysis of circulating long non-coding RNAs (lncRNAs) represents a transformative approach for the non-invasive management of hepatocellular carcinoma (HCC).
Decoding HCC Heterogeneity: Single-Cell RNA Sequencing Reveals ncRNA Drivers of Tumor Progression and Therapy Resistance
This comprehensive review explores the critical role of single-cell RNA sequencing (scRNA-seq) in unraveling non-coding RNA (ncRNA) heterogeneity in Hepatocellular Carcinoma (HCC).
LncRNAs as Clinical Tools: From Discovery to Diagnostic Validation in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, largely due to late-stage diagnosis.
A Comprehensive Guide to lncRNA In Situ Hybridization in Hepatocellular Carcinoma: From Basic Protocol to Clinical Validation
This article provides a comprehensive methodological framework for researchers and drug development professionals aiming to precisely localize long non-coding RNAs (lncRNAs) in hepatocellular carcinoma (HCC) tissues using in situ hybridization...
Leveraging lncRNA Expression Panels for Early Hepatocellular Carcinoma Detection: From Biomarker Discovery to Clinical Application
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, largely due to late-stage diagnosis.
LncRNA Classification and Molecular Functions in Hepatocellular Carcinoma: From Mechanisms to Precision Therapeutics
Hepatocellular carcinoma (HCC) remains a global health challenge with high mortality, driving urgent need for novel diagnostic biomarkers and therapeutic strategies.
Revolutionizing HCC Diagnosis: Machine Learning Integration of lncRNA Biomarkers
Hepatocellular carcinoma (HCC) remains a leading cause of cancer mortality globally, largely due to limitations in early detection.