Research Articles
Comparative Lipidomics in Type 1 and Type 2 Diabetes: Distinct Molecular Signatures and Pathways for Precision Medicine
This article provides a comprehensive comparative analysis of lipidomic profiles in Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D), synthesizing recent findings from clinical studies to elucidate distinct pathophysiological...
Overcoming Complex Lipidomes Coverage Limitations: Advanced Strategies for Biomarker Discovery and Clinical Translation
This article provides a comprehensive guide for researchers and drug development professionals tackling the central challenge in lipidomics: achieving comprehensive coverage of complex lipidomes.
Decoding Lipidomes: A Comprehensive Guide to Lipid Species Identification via MS/MS Fragmentation Patterns
This article provides a systematic overview of modern strategies for lipid species identification using tandem mass spectrometry (MS/MS).
Batch Effect Correction in Lipidomics: A 2025 Guide to Robust Data Analysis for Biomarker Discovery
This article provides a comprehensive guide for researchers and drug development professionals on managing batch effects in lipidomics data analysis.
Optimizing Lipid Extraction from Plasma and Serum: A Comprehensive Guide for Robust Lipidomics
Lipidomic analysis of plasma and serum is crucial for discovering biomarkers and understanding disease mechanisms in biomedical research.
Ensuring Reliability in Untargeted Lipidomics: A Comprehensive Guide to Quality Control Strategies for Robust Biomarker Discovery
Untargeted lipidomics provides a powerful, unbiased approach for discovering novel lipid biomarkers and pathways, but its potential is heavily dependent on rigorous quality control to ensure data reliability and reproducibility.
Navigating Biological Variability in Lipidomics: From Experimental Design to Clinical Translation
Lipidomics, the large-scale study of lipid pathways and networks, is increasingly recognized for its role in precision health, with profiles often predicting disease onset years earlier than genetic markers.
Standardizing Lipidomic Protocols for Clinical Samples: A Roadmap from Bench to Bedside
This article provides a comprehensive guide for researchers and drug development professionals on standardizing lipidomic protocols for clinical samples.
Navigating the Reproducibility Crisis in Lipidomic Biomarker Validation: From Foundational Challenges to Clinical Translation
Lipidomics has emerged as a powerful tool for discovering biomarkers that reflect real-time metabolic states in diseases ranging from cancer to inflammatory disorders.
A Comprehensive Guide to Lipidomics Workflows: From Sample Collection to Data Analysis
This article provides a detailed guide to lipidomics workflows, tailored for researchers, scientists, and drug development professionals.