Research Articles
A Comprehensive UHPLC-MS/MS Lipidomics Protocol: From Foundational Principles to Clinical Biomarker Validation
This article provides a detailed protocol for ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) in lipidomics, tailored for researchers, scientists, and drug development professionals.
Untargeted Lipidomics with UHPLC-Q-Exactive MS: A Comprehensive Workflow for Diabetes Biomarker Discovery and Metabolic Pathway Analysis
Untargeted lipidomics utilizing UHPLC-Q-Exactive MS technology has emerged as a powerful strategy for uncovering the complex lipid dysregulation associated with diabetes mellitus and its complications.
UHPLC-MS/MS Plasma Lipidomics in Diabetes Research: Methods, Applications, and Biomarker Discovery
This article provides a comprehensive resource for researchers and scientists on the application of Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry (UHPLC-MS/MS) for plasma lipid analysis in diabetes mellitus.
Lipidomics in Focus: Decoding the Pathophysiology of Hyperuricemia Complicating Diabetes
This article synthesizes current lipidomic research to elucidate the complex pathophysiology linking hyperuricemia and diabetes mellitus.
Dysregulated Lipidomic Signatures in Diabetic Patients with Hyperuricemia: Mechanisms, Biomarkers, and Therapeutic Implications
This article synthesizes current research on the distinct lipidomic profiles in diabetic patients with concurrent hyperuricemia, a high-risk clinical phenotype.
Lipid Metabolic Pathways in Hyperuricemia Patients with Diabetes: Molecular Mechanisms, Biomarkers, and Therapeutic Targeting
This article synthesizes current research on the intricate crosstalk between lipid metabolism and hyperuricemia in diabetic patients.
Lipidomics Biomarker Discovery in Diabetes and Hyperuricemia: From Pathophysiological Insights to Clinical Translation
This article provides a comprehensive exploration of lipidomics in the context of the co-occurrence of diabetes mellitus (DM) and hyperuricemia (HUA), a prevalent and clinically significant metabolic constellation.
Plasma Untargeted Lipidomics in Diabetes Mellitus and Hyperuricemia: Metabolic Signatures, Analytical Strategies, and Clinical Translation
This comprehensive review synthesizes current evidence from lipidomics studies on the complex interplay between diabetes mellitus (DM) and hyperuricemia (HUA).
Lipidomic Signatures in Type 2 Diabetes and Hyperuricemia: Molecular Insights, Biomarker Discovery, and Therapeutic Avenues
This article synthesizes current lipidomics research on the complex interplay between type 2 diabetes mellitus (T2DM) and hyperuricemia (HUA), a common and clinically significant comorbidity.
Dysregulated Lipid Metabolites in Diabetes and Hyperuricemia: Molecular Mechanisms, Analytical Approaches, and Therapeutic Implications
This comprehensive review examines the intricate relationship between dysregulated lipid metabolism, type 2 diabetes mellitus (T2DM), and hyperuricemia (HUA) through a multi-omics lens.