Research Articles
Head-to-Head Comparison of ncRNA Panels for Early HCC Detection: A Roadmap for Researchers and Developers
Hepatocellular carcinoma (HCC) is a global health threat with a poor prognosis, largely due to late diagnosis.
LINC00152 as an Independent Prognostic Biomarker in Hepatocellular Carcinoma: From Mechanistic Insights to Clinical Application
This comprehensive review synthesizes current evidence on the long non-coding RNA LINC00152 as a potent independent prognostic biomarker in hepatocellular carcinoma (HCC).
Circular RNAs vs. Long Non-Coding RNAs: A Comparative Analysis of Stability in HCC Liquid Biopsy
Liquid biopsy has emerged as a transformative, non-invasive approach for the management of hepatocellular carcinoma (HCC).
Validating lncRNA Prognostic Signatures in Hepatocellular Carcinoma: From Bench to Bedside
Hepatocellular carcinoma (HCC) remains a leading cause of cancer mortality worldwide, with a 5-year survival rate below 20% for advanced-stage patients.
Independent Prognostic lncRNA Biomarkers in HCC: From Multivariate Cox Validation to Clinical Translation
This article synthesizes current advancements in validating long non-coding RNA (lncRNA) biomarkers for hepatocellular carcinoma (HCC) prognosis using multivariate Cox regression models.
Single vs. Combined lncRNA Biomarkers in HCC: A Comprehensive Review of Diagnostic and Prognostic Efficacy
Hepatocellular carcinoma (HCC) is a global health challenge with high mortality, largely due to late diagnosis.
Tissue vs. Circulating lncRNAs: A Comparative Analysis for Advancing Hepatocellular Carcinoma Diagnosis
Hepatocellular carcinoma (HCC) presents a significant global health burden, with poor prognosis often due to late diagnosis.
Solving Low RNA Yield from Small HCC Biopsies: A Researcher's Guide to Optimization and Validation
This article provides a comprehensive guide for researchers and drug development professionals facing the challenge of low RNA yield from small hepatocellular carcinoma (HCC) biopsies.
SNHG16 as an Independent Prognostic Marker in HCC: From Molecular Mechanisms to Clinical Application
Hepatocellular carcinoma (HCC) is a lethal malignancy with a high recurrence rate and poor survival.
Beyond AFP: LncRNAs as Superior Prognostic Biomarkers in Hepatocellular Carcinoma
Alpha-fetoprotein (AFP), the conventional serological biomarker for Hepatocellular Carcinoma (HCC), is hampered by limited sensitivity and specificity, fueling the search for more reliable alternatives.