Research Articles
CRISPR-Cas9 in Genetic Disorder Therapy: From Molecular Tools to Clinical Breakthroughs
This article provides a comprehensive overview of the transformative role of CRISPR-Cas9 gene-editing technology in treating genetic disorders.
Validating the AmpliSeq for Illumina Childhood Cancer Panel: A Comprehensive Framework for Clinical and Research Applications
This article provides a detailed validation framework for the AmpliSeq for Illumina Childhood Cancer Panel, a targeted NGS solution for pediatric and young adult cancers.
Isothermal Amplification in Molecular Point-of-Care Testing: A Comprehensive Guide for Researchers and Developers
This article provides a comprehensive analysis of isothermal nucleic acid amplification technologies (INAATs) for molecular point-of-care (POC) diagnostics, tailored for researchers, scientists, and drug development professionals.
RAA-Strip Technology for African Swine Fever Virus: A Comprehensive Guide to Point-of-Care Molecular Detection
This article provides a comprehensive analysis of Recombinase Aided Amplification (RAA) coupled with lateral flow strips (LFS) for the point-of-care detection of African Swine Fever Virus (ASFV).
Unveiling the Hidden: A Comprehensive Guide to Rare Cell Type Identification in Single-Cell RNA-Seq Analysis
This article provides a comprehensive resource for researchers and drug development professionals aiming to identify and characterize rare cell populations from single-cell RNA sequencing data.
Precision Quantification of CCR5Δ32 Mutant Alleles in Heterogeneous Cell Populations Using Droplet Digital PCR
This article provides a comprehensive resource for researchers and drug development professionals on the application of droplet digital PCR (ddPCR) for the precise quantification of the CCR5Δ32 mutant allele in...
Advanced Optimization Techniques for Protein Structure Determination from X-ray Crystallography Data
This article provides a comprehensive guide for researchers and drug development professionals on optimizing protein structure determination using X-ray crystallography.
Protein-Small Molecule Interactions: Mechanisms, Methods, and Advances in Drug Discovery
This article provides a comprehensive overview of the molecular basis of protein-small molecule interactions, a cornerstone of structural biology and rational drug design.
Advancing SARS-CoV-2 Detection: A Comprehensive Guide to Highly Sensitive One-Step Nested RT-PCR
This article provides a thorough examination of One-Step Nested Reverse Transcription PCR (OSN-RT-PCR) for the detection of SARS-CoV-2, catering to researchers, scientists, and drug development professionals.
Revolutionizing Neuropharmacology: Advances in 3D Bioprinted Blood-Brain Barrier Models for Drug Discovery
The blood-brain barrier (BBB) represents a major challenge in developing therapeutics for central nervous system diseases.